Stan Lee

Tobey Maguire Spider-Man / Peter Parker

Willem Dafoe Green Goblin / Norman Osborn

Kirsten Dunst Mary Jane Watson

James Franco Harry Osborn

Cliff Robertson Ben Parker

Rosemary Harris May Parker

J.K. Simmons J. Jonah Jameson

Joe Manganiello Flash Thompson

Gerry Becker Maximilian Fargas

Bill Nunn Joseph 'Robbie' Robertson

Jack Betts Henry Balkan

Stanley Anderson General Slocum

Ron Perkins Dr. Mendell Stromm

Michael Papajohn Carjacker

K.K. Dodds Simkins

Ted Raimi Hoffman

Bruce Campbell Ring Announcer

Elizabeth Banks Betty Brant

John Paxton Houseman

Tim De Zarn Philip Watso

Taylor Gilbert Madeline Watson

Randy Savage Bone Saw McGraw

Larry Joshua Wrestling Promoter

Timothy Patrick Quill Wrestling Arena Guard

Lisa Danielle Bone-ette

Natalie T. Yeo Bone-ette

Erica D. Porter Bone-ette

Kristen Davidson Bone-ette

Jason Padgett Flash's Crony

Shan Omar Huey Teacher

Sally Livingstone Girl on Bus

Evan Arnold Doctor

Jill Sayre Nurse

James Kevin Ward Project Coordinato

David Holcomb Test Pilot

Octavia Spencer Check-In Girl

Brad Grunberg Heckler

Shane Habberstad Little Billy

Deborah Wakeham Billy's Mom

Rachael Bruce Times Square Child

Mackenzie Bryce Times Square Child

Julia Barry Times Square Child

Macy Gray Herself

Myk Watford Cop at Fire

Bill Calvert Firema

Sylva Kelegian Mother at Fire

Kristen Marie Holly Young Lady at Fire

Ajay Mehta Cabbie

Peter Appel Cabbie

Scott Spiegel Marine Cop

Matt Smith Cop at Carjacking

Sara Ramirez Cop at Carjacking

Lucy Lawless Punk Rock Girl

Jayce Bartok Subway Guitarist

Maribel Gonzalez Lady Dogwalke

Amy Bouril Office Lady

Joe D'Onofrio Opinionated Co

Jim Norton Surly Truck Driver

Corey Mendell Parker Chaperone in Tram

Ashley Edner Girl in Tra

William Joseph Firth Boy in Tram

Alex Black Boy in Tram

Laura Gray Tram Group Mother

Joe Virzi New Yorker on Bridge

Michael Edward Thomas New Yorker on Bridge

Jeanie Fox New Yorker on Bridge

Robert Kerman Tugboat Captain

Ari Averbach Dancer (uncredited)

Joni Avery Cop (uncredited)

Rick Avery Cop (uncredited)

Margaret Baker Punk #2 (uncredited)

Amy Beth Bennett Jewelry Thief #2 (uncredited)

Brian Bennett Doorman (uncredited)

Camille Bennett High School Student (uncredited)

Andy Bray Boy carrying tray in Cafeteria (uncredited)

Jophery C. Brown Chef (uncredited)

Jacob Chambers Cop (uncredited)

Jillian Clare Crying Girl in Tram (uncredited)

Chris Coppola Kyle (uncredited)

Cody Cundiff World Unity Day attendee (uncredited)

Una Damon Lab Tour Guide (uncredited)

Chandra De Alessandro Cop (uncredited)

Mark De Alessandro Cop (uncredited)

Michael Patrick Dobkins Wrestiling Fan (uncredited)

Patrick Coleman Duncan Oscorp Lab Technician (uncredited)

Marcus Edward Screaming Fan at Wrestling Match (uncredited)

R.C. Everbeck Eddie Brock (scenes deleted) (uncredited)

Peter Genovese Fleeing World Unity Day Patron (uncredited)

Marcus Gorman Man in Street (uncredited)

Al Goto Cop (uncredited)

Juan M. Guerra City guy (uncredited)

Randy Hall Cop (uncredited)

Jesse Heiman Spectator at the scholl's fight. (uncredited)

Tia Dionne Hodge Uptown Woman (uncredited)

Kevin Jackson Bellman (uncredited)

Loren Janes Board of Directors Member (uncredited)

Andray Johnson Balkan's Aide (uncredited)

Claudia Katz Robbie's Assistant (uncredited)

Erik Kleven Chef (uncredited)

Pete Macnamara Pentagon Officer (uncredited)

Joy Michelle Moore World's Fair mom (uncredited)

Justin Neill Flash's Crony (uncredited)

Philip Ng Diamond District Attendee (uncredited)

Debra Orenstein Doctor (uncredited)

Gary Otto New Yorker (uncredited)

Leroy Patterson World Unity Festival Attendant (uncredited)

Martin Pfefferkorn Thug on 8x10 (uncredited)

Lance Polland Bonesaw Fan (uncredited)

January Pugh Mary Jane's Friend (uncredited)

Sumner Redstone Oscorp Board Member (uncredited)

Scott L. Schwartz Screaming Wrestler (uncredited)

Robair Sims Bellman (uncredited)

Richard Stephens Man on Brooklyn Bridge (uncredited)

Tammi Sutton Street Vendor (uncredited)

Lindsay Thompson Mary Jane's Friend (uncredited)

Lou Torres Enrique (uncredited)

Brigid Turner Featured Hot Girl (uncredited)

Benny Urquidez Mugger (uncredited)

Sean Valla Boat Light Man (uncredited)

Derek C. Wallace Homeless Man (uncredited)

John Wojnowski III Man in Street (uncredited)