Justin W. Chambers (born July 11, 1970) is an American actor and former Calvin Klein male fashion model.
Chambers was born in Springfield, Ohio, the son of deputy police officers Pam and John Chambers. He has a twin brother named Jason, one older brother Chip; and two older sisters, Mia and Susan. He and his twin brother visited hospitals often as children due to frequent bouts with pneumonia. He attended Springfield Christian elementary school.
He has five children with his wife, Keisha: Isabella (1995), the twins Maya and Kaila (1999), Eva (2001) and Jackson (2002). Keisha is a former model agency booker whom he married in 1993. His wife and children have recently moved to Los Angeles from their home in a suburb just outside of New York City.
Chambers was discovered by a modeling scout on the Paris Metro and went on to represent Calvin Klein in a fragrance campaign. He worked throughout Europe, Japan, and the United States for CK, Armani, and Dolce & Gabbana.
After deciding on an acting career, he moved to New York, where he studied at H.B. Studios for four years. That landed him a few television roles, including Another World and New York Undercover. More recently, he starred in several movies, notably The Wedding Planner, The Musketeer, Southern Belles, The Zodiac, Lakeview Terrace and the HBO original movie Hysterical Blindness. Chambers was cast as one of the leads in the CBS crime drama Cold Case but left after appearing in only four episodes.
Now he plays resident Alex Karev on the hit ABC medical show Grey's Anatomy.
His first major acting role came in the music video "Ants Marching" by Dave Matthews Band in 1994.