The story follows a mercenary named Royce who is abducted by alien creatures known as the Predators. He is released onto an alien planet-which acts as a game reserve-along with seven other humans, who, with the exception of a disgraced physician, are all cold-blooded killers, the group consisting of mercenaries and convicts. Royce reluctantly leads the group of elite warriors as they come to realize they have been brought together to this planet as prey for a new breed of Predator.